Marco Rubio continually loses his way and forgets that the main stream of American society is feeling alienated and disenfranchised. And it seems that Rubio can be bought and will change, chameleon-like, depending on who he is talking to and what he hopes to benefit from them.
Of course, the biggest mistake he made is with the Gang of Eight and the amnesty program. He made common cause with Democrats who want lots of new Latino voters who will be Democrats for life if they are given amnesty. He did this to unite with big business, which means donors, who want cheap labor. He ignored the fact that millions of illegal immigrants are flooding the country, taking jobs that Americans will do, taking lots of government services, and disrupting societies and standards. There is no attempt to assimilate, only to impose. Rubio later tried to explain after it cost him his credibility, but he was caught lying. His believability has sunk to new lows, and now he has decided to throw in with another group that is not interested in assimilating. He is simply digging a bigger and bigger hole.
Rubio against U.S. citizens again, page 2:

Rubio, your stupid
A=hole
Which end of the range they stand on
idiot.
F##$ YOU !
Fearing people who might be trying to kill you all this time I thought that was called SANITY.
they make good targets
Yea, they make great targets.
There was once a time when men of the cross became nights of the cross, the difference between them and their fellow Christians was they were willing to pick up the sword and place themselves between the Ungodly and God’s children.
There is a savage in all of us, but a savage under God is the righteous wrath of the faithful. He is but the sword God wields and only as sharp as his faith is strong.
This is another reason that Rubio had no fans and dropped out of the race.